Papers The RECOMB conference series was founded in 1997 to provide a scientific forum for communicating advances in computational biology and applications in molecular biology and medicine. The conference aims at bridging the computational, mathematical, statistical, and biological sciences, and bringing together researchers, professionals, students and industrial practitioners from all over the world for interaction and exchange of new developments in all areas of bioinformatics and computational biology. The conference will feature keynote talks by leading scientists, presentations of peer-reviewed high-quality research papers, presentations of exciting research developments that were published within the past year and poster sessions on latest research progress. Topics Papers reporting on original research (both theoretical and experimental) in all areas of computational molecular biology are suitable for submission. Topics of interest include, but are not limited to: Molecular sequence analysis Sequencing and genotyping technologies Gene regulation and epigenomics Transcriptomics, including single-cell Metagenomics Population and statistical genetics Evolution and comparative genomics Structure and function of non-coding RNAs Computational proteomics and proteogenomics Computational structural biology Computational metabolomics Protein structure and function Biological networks Computational systems biology Privacy of biomedical data Bioimaging