The IEEE LCN 2025 conference seeks papers presenting significant research contributions in theoretical and practical aspects of computer networking. LCN is a highly interactive conference that enables an effective exchange of research outcomes and ideas among academics, research students, and industry. For the past 49 years, major developments from network protocols, sensor networks to AI supported networking and emerging areas like quantum networking have been reported at this conference. LCN welcomes submissions on wide range of computer networking research, including but not limited to the following: Adaptive networking applications AI-enabled networking Cognitive radio networks Cross-layer optimization Cyber-physical systems Data center networking Decentralized Systems and Blockchain Networks Delay-tolerant networks Digital Twins Edge and Cloud computing E-Health networking Embedded networks Green and sustainable networking Information-centric networking Internet of Things Local area networks Large Language Models (LLMs) and generative AI for networking Machine-to-machine communications for smart environments Mobile and ubiquitous networking Mobility and Location-dependent services Networking for Virtual, Augmented, Mixed Reality applications Network coding Network management, reliability and QoS Network security and privacy Network traffic characterization and measurements Opportunistic networking Optical and high-speed access networks Overlay and peer-to-peer networks Performance evaluation of networks Personal and wearable networks Quantum communication and networking Routing and transport protocols Satellite communication and networks Smart Cities, Buildings and Districts Smart Grid communications Social networks Software Defined Networking and Network Function Virtualization Test beds for network experiments Underwater sensor networks Vehicular networks Wireless ad hoc & sensor networks Semantic communication